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These nocturnal leg cramps affect 50-60% of healthy adults

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In the NEJM Phase 2 trial, participants assigned to an initial dose of 4 mg experienced significantly more adverse events than those who started at 2 mg, even when both groups ultimately reached the same target dose

Daily equimolar dosing of gel-forming drops (freshly prepared every 14 days) containing the polymer only (vehicle) or with 112 mM NAC or 112 mM NACET (21.5 mg/mL) was initiated when the eyes opened at P14

hiPSCs hold great promise for fabricating whole organs from patients' own cells, obviating the current limitations of immunogenic rejection and donor organ shortages

Whilst the liver stores several years' worth of vitamin B12, concerns arise about whether fat accumulation might impair this function