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Chao Zhong et al

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24R,25(OH) 2 D 3 , 24R,25-dihydroxyvitamin D 3

The biosynthetic incorporation of these PUFAs into phospholipids requires two key enzymes: acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3)

While not FDA-approved, MK-677 has been used extensively in clinical trials and is considered well-tolerated in most populations when dosed responsibly