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Although crosstalk between BH 4 /CoQ 10 and xCT/GPX4 pathways, which reduces lipid peroxidation and ferroptosis, has been reported, further studies are needed to investigate the anti-ferroptotic properties of the BH 4 /CoQ 10 system

However, p53 deletion-induced non-small cell lung carcinoma (NSCLC) is sensitive to the disruption of BCAT1/2 because the high expression of BCAA catabolic enzymes leads to active use of BCAAs (Mayers et al., 2016)

Abstract Glutathione is primarily known as a cellular antioxidant molecule, but its role in lateral root development in rice plants has not been elucidated

More serious but rare adverse events include pancreatitis (0.2% incidence), gallbladder disease requiring surgical intervention, and medullary thyroid carcinoma risk in genetically predisposed individuals (contraindicated in patients with personal or family history of MTC or MEN2 syndrome)

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

Role of glutathione metabolism in host defense against Borrelia burgdorferi infection