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Despite these advances, clinical deployment of AI models remains constrained by uneven data quality, algorithmic bias, and a paucity of large-scale external validation

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They are rapidly absorbed, with measurable levels appearing in the bloodstream shortly after ingestion, making them highly effective for nutritional and therapeutic applications [66]

The underlying molecular mechanisms involve direct ROS-induced oxidative damage to neuronal lipids, proteins and DNA [331], as well as ROS-mediated oxidative modifications that crucially promote the aberrant aggregation of toxic proteins [332]