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Arg147His Polymorphism: Bone fractures in Japanese postmenopausal females Allelic disorder: Ataxia, Myoclonus, Exercise intolerance SLC25A32 protein Nosology: Mitochondrial folate transporter (MFT) Folate transporter: Cytoplasm to Mitochondria Location: Inner mitochondrial membrane Clinical Onset age: 2nd decade Exercise intolerance: Recurrent Treatment: Riboflavin Laboratory Biochemistry: Multiple acyl-coenzyme A dehydrogenase deficiency (MADD) pattern Muscle Lipid: Type I fibers, Mild increase Type II fibers:

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Activation of cGAS-STING signaling can also activate a variety of immune cells including DCs, macrophages, NK cells, CD4 + and CD8 + T cells by triggering the relevant natural immune signals, leading to reduction or even complete disappearance of a variety of tumors in vivo ( 81)

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