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CRediT authorship contribution statement Bing Cheng: Writing original draft

The reviewer ZC declared a shared affiliation with the author(s) TS to the handling editor at the time of review

Indeed, a decrease in the carnitine-dependent fatty acid transport system causes an accumulation of acyl-CoA molecules in the cytosol, and these metabolites inhibit the urea cycle ( Malaguarnera, 2013 )