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Six cancer types were analyzed: LGG: Brain Lower Grade Glioblastoma, CHOL: Cholangiocarcinoma, HNSCC: Head and Neck Squamous Cell Carcinoma, GBM: Glioblastoma, KIRC: Kidney Renal Clear Cell Carcinoma, and AML: Acute Myeloid Leukemia

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In summary, the functional transition of RIPK1 can lead to three different outcomes: survival, necroptosis, and apoptosis

Shao et al

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Meanwhile, mitochondrial respiration was impaired by PA followed by decreased ATP turnover, increased maximal respiration, and proton leak (132)