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Description

J Mol Med

Research Highlights Metabolic Regulation and Anti-Obesity Effects: Potent inhibition of nicotinamide N-methyltransferase (NNMT) increases cellular NAD and S-adenosylmethionine (SAM) levels, enhances polyamine flux, boosts energy expenditure, and suppresses lipogenesis

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However, when combined with HA, the drug may remain longer in the joint cavity, increasing bioavailability and therapeutic potential

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