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Although there is no close relationship between plasma VPA concentrations and the severity of CNS toxicity [11, 86], patients who ingest more than 200 mg/kg VPA and/or have plasma concentrations greater than 180 g/ml usually develop severe CNS depression

Cancer pharmacomicrobiomics: targeting microbiota to optimise cancer therapy outcomes

[Epub ahead of print] Lee W

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Their reduction may reflect disrupted arachidonic acid-related lipid signaling and broader alterations in lipidamino acid metabolism in MMA [32]

neoformans To find genetic elements controlling sulfur amino acid biosynthesis, we studied a gene annotated as CYS3