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Shao CY, Mirra SS, Sait HB, Sacktor TC, Sigurdsson EM

387 IL-15 is critical for enhancing the development and functional efficacy of CD8 + T cells

doi: 10.1016/j.mrgentox.2016.05.003 114 HintonAON'JaiAUVueZWanjallaC

The peptide has also never been characterized in humans the way an approved drug is: there is no established human pharmacokinetic profile, no dose-ranging efficacy study, and no long-term safety dataset