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Regardless, taken together with the metabolic incorporation of Neu5Gc, Neu5Gc-containing glycans appear to act as xenoautoantigens that can be targeted by naturally circulating anti-Neu5Gc xenoautoantibodies, leading to an inflammatory process termed xenosialitis (Hedlund et al., 2008

Microbiome 5 , 14 (2017)

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Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

PMID: 41605214 Cell Metab Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11