Abbreviations ASL: Airway surface liquid ALI: Airliquid interface COPD: Chronic obstructive pulmonary disease WHO: World health Organization PM: Particulate Matter AED: Aerodynamic equivalent diameter ROS: Reactive oxygen species RNS: Reactive nitrogen species NAC: N-acetylcysteine hNEC: Human nasal epithelial cell poly I:C: Polyinosinic:polycytidylic acid HDM: House dust mite BaP: Benzo[a]pyrene CYP27B1: 1-Hydroxylase RSV: Respiratory syncytial virus hBEC: Human bronchial epithelial cell LPS: Lipopolysaccharide BALF: Bronchoalveolar lavage fluid TH17: T helper 17 DEP: Diesel exhaust particle EMT: Epithelial-mesenchymal transition CSE: Cigarette smoke extract GSH/GSSG: Glutathione (reduced/oxidized) CF: Cystic fibrosis IPF: Idiopathic pulmonary fibrosis References Yang W
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Stress, infections and certain medications can contribute to outbreaks
Genomics 1996;33:498-507
Patients with severe comorbidities, such as liver and kidney dysfunction, systemic infection or inflammation, blood system diseases, malignancies, autoimmune diseases, and mental disorders, were excluded
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