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Preclinical studies in rodents with pilocarpine- and kainate-induced temporal lobe epilepsy showed high levels of ROS/RNS, lipid peroxidation with consequent hippocampal apoptosis, damage of membranes and organelles, protein synthesis in survived neurons and altered gene expression, and GSH action was reduced extensively (Atanasova et al., 2013, Pearson et al., 2015)

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In the present study, we measured iron and TF levels in AH collected during cataract surgery from control subjects and patients with AMD, stratified following the recent CAM classification in drusen without any signs of atrophy, iRORA, and cRORA depending on the extension of the RPE and outer retinal atrophy based on SD-OCT [33,34,35]

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Structure-function relations of human hemoglobins

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